Re: Overdiagnosis in Cancer
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چکیده
منابع مشابه
Re: overdiagnosis and overtreatment in cancer: an opportunity for improvement.
Expert’s summary: One of the major goals of improving the survival rate for many common cancers has been seeking an earlier diagnosis. The concept has been that ifwe candiagnose cancers earlier,we can treat them before metastasis occurs, and the survival rates will increase. Unfortunately, despite the rapid introduction and use of prostate-specific antigen (PSA) testing, chest and abdominal ima...
متن کاملOverdiagnosis in cancer.
This article summarizes the phenomenon of cancer overdiagnosis-the diagnosis of a "cancer" that would otherwise not go on to cause symptoms or death. We describe the two prerequisites for cancer overdiagnosis to occur: the existence of a silent disease reservoir and activities leading to its detection (particularly cancer screening). We estimated the magnitude of overdiagnosis from randomized t...
متن کاملConceptualizing overdiagnosis in cancer screening.
The aim of cancer screening is to detect asymptomatic cancers whose treatment will result in extension of life, relative to length of life absent screening. Unfortunately, cancer screening also results in overdiagnosis, the detection of cancers that, in the absence of screening, would not present symptomatically during one's lifetime. Thus, their detection and subsequent treatment is unnecessar...
متن کاملRe: Extended lung cancer incidence follow-up in the Mayo Lung Project and overdiagnosis.
Marcus et al. ( 1 ) are to be commended for successfully carrying out the follow-up of the 1983 survivors of the Mayo Lung Project. We question, however, whether overdiagnosis of screening-detected lung cancer is a necessary or sufficient explanation of the observed results. If we assume that successful randomization resulted in two study arms with a similar risk of lung cancer throughout follo...
متن کاملEstimation of Overdiagnosis in Breast Cancer Screening
I. Summary The benefit of breast cancer (BC) screening with mammography has been demonstrated by randomized controlled trials (RCTs). However, there is a growing concern about the harms of screening, in particular the problem of overdiagnosis. It occurs when screening detects a breast cancer that would not have presented clinically in the woman's lifetime in the absence of screening. Overdiagno...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2010
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djq410